THIS CASE REPORT PRESENTS A 63-YEAR-OLD FEMALE PATIENT WHO INITIALLY PRESENTED WITH A GRADUALLY ENLARGING, SMOOTH-WALLED, FIRM, TENDER, FLESHY MASS AT THE LEFT MANDIBULAR ALVEOLAR AREA, WITH AN INITIAL HISTOPATHOLOGY OF NEUROFIBROMA. AFTER BIOPSY, THE MASS RAPIDLY INCREASED IN SIZE, NEARLY OBSTRUCTING ORAL CAVITY OPENING, RESULTING TO DIFFICULTIES IN SWALLOWING AND BREATHING. PATIENT UNDERWENT A SERIES OF SURGERIES AND BIOPSIES DUE TO PRECIPITOUSLY RECURRING MASS. ON FINAL HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL EXAMINATION, THE CASE WAS SIGNED OUT AS LEIOMYOSARCOMA. LEIOMYOSARCOMA IN THE MANDIBLE IS EXTREMELY RARE AND THERE ARE INSUFFICIENT CASES REPORTED IN LITERATURE, RESULTING TO SIGNIFICANT DIAGNOSTIC AND THERAPEUTIC CHALLENGE IN CLINICAL PRACTICE. THE FINDINGS IN THIS CASE REPORT MAY EXPAND OUR KNOWLEDGE AND DIRECT OUR DECISION-MAKING TO IMPROVE THE DIAGNOSIS AND MANAGEMENT OF A RECURRENT, UNILATERAL MASS IN THE MANDIBLE.