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EFFECTS OF MULTIMODAL ACOUSTIC THERAPY ON MUSIC AND SPEECH PERCEPTION IN PEDIATRIC COCHLEAR IMPLANT USERS: A DOUBLE-BLIND; RANDOMIZED CONTROLLED TRIAL
SENSORY ORGAN RESEARCH INSTITUTE, SEOUL NATIONAL UNIVERSITY MEDICAL RESEARCH CENTER, SEOUL, REPUBLIC OF KOREA 1, BELL THERAPEUTICS INC, SEOUL, REPUBLIC OF KOREA 2, INTELLIGENCE AND INTERACTION RESEARCH CENTER, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, SEOUL, REPUBLIC OF KOREA 3, DEPARTMENT OF MUSICOLOGY, SEOUL NATIONAL UNIVERSITY, SEOUL, REPUBLIC OF KOREA 4, DEPARTMENT OF MUSIC TECHNOLOGY, KOREA NATIONAL UNIVERSITY OF ARTS, SEOUL, REPUBLIC OF KOREA5, DEPARTMENT OF OTORHINOLARYNGOLOGY-HEAD AND NECK SURGERY, SEOUL NATIONAL UNIVERSITY HOSPITAL, SEOUL NATIONAL UNIVERSITY COLLEGE OF MEDICINE, SEOUL, REPUBLIC OF KOREA.6
MINYOUNG SHIN, MINYOUNG SHIN1,2, JEONG MI PARK2,4, JONGHWA PARK2,3, JIYEON HA2, WONWOO LEE2,5, SANG-YEON LEE6
¸ñÀû: Pediatric cochlear implant (CI) users often face difficulties in music perception and speech recognition even after prolonged CI usage. Effective and innovative auditory rehabilitation strategies are essential to address these limitations. To assess the efficacy of a novel digital app-based rehabilitation that integrates verbal and non- verbal auditory training, called Multimodal Acoustic Therapy (MAT), on music and speech perception in pediatric CI users. ¹æ¹ý:A double-blind, randomized controlled trial was conducted from July to October 2024. Forty-two pediatric CI users (aged 8 to 20 years) were recruited from Seoul National University Hospital, Korea. Eligibility criteria included a minimum of two years of CI use, native Korean language proficiency, and familiarity with smartphone use, while individuals with severe comorbidities, cognitive deficits, emotional disorders, or reliance on sign language were excluded. Thirty-three participants were randomly assigned to either the MAT intervention group (n = 16) or the active control (AC) group (n = 17), which used a curated music streaming platform. Primary outcome measures included music perception assessed via the Melodic Contour Identification (MCI) test and speech perception evaluated through vowel, consonant, and monosyllabic word recognition tests. °á°ú:Of the 42 enrolled pediatric CI recipients, 28 completed the intervention and were analyzed (MAT group; n=13, AC group; n=15). The MAT group showed a significant improvement in MCI scores (mean difference [MD], 11.5%; 95% CI, −22.4% to 45.3%; P < .05) compared to the AC group (MD, 0.2%; 95% CI, −31.4% to 31.7%). Similarly, speech perception improved significantly in the MAT group for consonant identification (MD, 14.1%; 95% CI, −4.7% to 32.9%) but not in the AC group (MD, 5.9%; 95% CI, −11.5% to 23.4%). Additionally, within the MAT group, vowel and monosyllable test scores showed significant enhancements (P < .05 for both), whereas the AC group exhibited no significant changes. °á·Ð:Multimodal acoustic training-based digital therapeutics yielded significant improvements in music and speech perception, suggesting its potential as a comprehensive and accessible rehabilitation method for pediatric CI users. This study introduced Multimodal Acoustic Therapy (MAT), a novel auditory rehabilitation method designed for cochlear implant users, employing a structured approach that integrates verbal and non-verbal sound training. Its effectiveness was assessed through a double-blinded randomized controlled trial, suggesting potential benefits for improving auditory outcomes in pediatric CI users. Developed as smartphone-based software, MAT provides convenience and scalability for clinical implementation. Future research with larger sample sizes and adult CI populations is necessary to further validate its efficacy and expand its clinical applications.


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