CHONDROLIPOMA ARISING IN THE EUSTACHIAN TUBE Abstract Introduction Only 15% of all lipomas are located in the head and neck region, most often involving the back of the neck. Lipoma is divided into several categories according to histological structure, including fibrous /fibro-/, spindle /spindle cell/, pleomorphic /pleomorphic/, muscle /myo-/, vascular /angio-/, chondroid /chondroid/, myxo, and bone lipoma. Chondrolipoma, a rare variant of lipoma, is a benign mesenchymal tumor rarely involving the nasopharynx. A rarer variant of lipoma, chondrolipomas are benign mesenchymal tumors. The proliferation of mature adipocytes forms them and contain different amounts of mature cartilaginous tissue; Weiss “ Enzinger and Weiss's soft tissue tumors”, 4th ed: Mosby, St Louis; 2001 Maybe, This represents the third reported case of a nasopharyngeal chondrolipoma. Case presentation In this case report, we describe the presentation and treatment of a patient with chondrolipoma arising in the eustachian tube. A 9-year- old girl was referred for ENT assessment with a 4-year history of increasing nasal congestion and hearing loss. Our patient was examined at our hospital, and nasal endoscopy revealed a nasopharynx mass, computed tomography revealed a well-defined, hypodense, lesion involving the left Eustachian tube and nasopharynx, measuring 1.4 × 2.1 cm. The mass was excised using an endoscopic approach and was found to originate from the cartilaginous portion of the Eustachian tube. The tumor was sent for histopathologic evaluation. Conclusion Chondrolipoma of the Eustachian tube is very rare compared with other types of lipomas. Improved radiologic modalities aid the diagnosis of this benign tumor. Endoscopic removal of the tumor is possible and has helped in early recovery. This is the first report of a lipoma originating from the cartilaginous portion of the Eustachian tube, and the tumor was removed successfully by an endoscopic approach at our hospital. Keywords: nasopharyngeal, eustachian tube, chondrolipoma