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ORAL MUCOSAL MELANOMA
DEP. OF HEAD AND NECK SURGERY, NATIONAL CANCER CENTER OF MONGOLIA1, DEP. OF PATHOLOGY, NATIONAL CANCER CENTER OF MONGOLIA2
BURENZAYA TUVDENDORJ, BURENZAYA TUVDENDORJ1, URANZAYA YUNGERMAA1, LUTZUL MENDBAYAR1, AMARSANAA GANTULGA1, YANJINLKHAM MUNKHBAYAR1, DENIS SKURATOV1, GANCHIMEG GANKHUYAG2
Oral mucosal melanoma is a rare, indolent malignant tumor. Early in the course of the disease, dark brown spots, nodules, or gray, red, or purple nodules or areas of depigmentation may be seen on the oral mucosa, and these changes tend to go unnoticed during oral and dental examinations. A 42-years-old Mongolian man, A bloody abscess appeared at the site of the tooth extraction in the left upper jaw. The upper left 1st and 2nd molars were extracted and were about 3x3cm in size, growing from the hard palate and the palatine fold towards the uvula, bluish-brown in color, rough, with a soft texture, bleeding easily from the bite, and having an unpleasant odor. Biopsy revealed melanoma, which was confirmed by additional immunohistochemistry. Molecular genetic analysis also revealed a BRAF gene mutation. The patient underwent a planned procedure under general anesthesia, in accordance with the National Comprehensive Cancer Network guidelines. Currently, the primary tumor has not recurred and distant metastasis of the tumor has not been identified. During the oral examination, it is important for professionals to pay close attention to both benign and malignant changes in the oral mucosa.


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