| 1DEPARTMENT OF OTORHINOLARYNGOLOGY-HEAD AND NECK SURGERY, NOWON EULJI MEDICAL CENTER, EULJI UNIVERSITY SCHOOL OF MEDICINE, SEOUL, REPUBLIC OF KOREA 2 EULJI TINNITUS AND HEARING RESEARCH INSTITUTE, NOWON EULJI MEDICAL CENTER, SEOUL REPUBLIC OF KOREA |
¸ñÀû: This study aimed to analyze the questionnaire results and behavioral
test outcomes of patients in Korea suspected of having auditory
processing disorder (APD), to identify their characteristics and
estimate the lesion sites ¹æ¹ý:The study included 48 participants with symptoms suggestive of APD,
and 30 control participants. All participants had an average pure-tone
audiometry threshold of <20 dB in both ears and a Mini-Mental State
Examination score of >27. The APD questionnaire, consisting of 25
items with a total score of 100, was developed based on the AAA
Clinical Practice Guideline, Auditory Processing Domains
Questionnaire, and the Speech and Spatial and Qualities of Hearing
Scale. The behavioral tests included: 1) 3-digit dichotic test, 2)
dichotic constant-vowel listening test, 3) frequency pattern test, 4)
temporal modulation transfer function test, 5) compression 60% speed
up listening test, and 6) speech-in-noise test. The criteria for
diagnosing APD were defined as scores more than 2 standard deviations
below the mean on at least two different behavioral test domains. °á°ú:Among the 48 participants, 39 (37.78 ¡¾ 9.93 years; M:F = 13:26) were
diagnosed with APD (APD+ group), while the remaining 9 subjects were
categorized as the APD- group. The APD+ and APD- groups scored (50.79
¡¾ 16.68 and 52.22 ¡¾ 17.37, respectively) higher than the normal
group (19.8 ¡¾ 11.79) on the questionnaire (p < 0.001), but there was
no significant difference between the APD+ and APD- groups. All tests,
except the temporal modulation transfer function test, showed
significantly poorer performance in APD+ group compared to the control
group (all p < 0.05). The questionnaire scores were well correlated
with almost all behavioral test scores. Based on the behavioral test
results, the estimated lesion locations were as follows: right
auditory cortex in 14 cases, right auditory cortex or corpus callosum
in 6 cases, left auditory cortex in 3 cases, left auditory cortex or
corpus callosum in 4 cases, corpus callosum in 1 case, and
indeterminate in 11 cases. °á·Ð:The study demonstrates that a significant portion of individuals in
Korea who self-report symptoms suggestive of APD actually have APD.
The findings also suggest that the right auditory cortex may be a
common lesion site in APD cases, although further research is needed
to confirm these results and better understand the underlying neural
mechanisms. |