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LETHAL MIDLINE GRANULOMA IN A 20-YEAR-OLD FILIPINO MALE PRESENTING AS AN ULCERATION ON THE NASOMAXILLARY AREA AND PALATE
DEP. OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY, EAST AVENUE MEDICAL CENTER
ALEXIS MA. BIANCA RAMIRO AMISOLA, ALEXIS MA. BIANCA R. AMISOLA, M.D.
This case report describes a 20-year-old male who presented with a five- month history of left nasal dorsum swelling, nasal obstruction, and watery nasal discharge, which later progressed to mucopurulent discharge and ulceration of the nasal dorsum. Initial antibiotic treatment provided minimal relief of symptoms, and a CT scan showed a heterogenously enhancing lesion occupying the left maxillary sinus and left nasal cavity. Biopsy revealed extranodal NK/T-cell lymphoma (ENKTCL), nasal type. Immunohistochemistry confirmed the NK/T-cell origin of the tumor, with CD3 and CD56 positivity. However, Epstein-Barr virus (EBV) testing was not conducted due to resource limitations. The patient was advised to undergo chemotherapy and radiation therapy. ENKTCL is a rare, aggressive lymphoma often associated with EBV, presenting with nasal obstruction, bloody rhinorrhea, and facial swelling. Early diagnosis and treatment are critical for improving outcomes.


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