¸ñÀû: To assess voice outcomes using the novel technique of in-office
laryngeal electromyography-guided vocal fold injections (LEVFI)
with
hyaluronic acid to treat glottal insufficiency. Secondary
objectives
included determining the complication/completion rates and if any
factors were associated with improved voice outcomes. ¹æ¹ý:Retrospective review of patients who received LEVFI at a tertiary
academic voice centre. Three and six-month voice outcomes were
assessed.
Outcomes included voice handicap index-10 (VHI-10), maximum
phonation
time (MPT), perceptual analysis of voice (GRBAS), fundamental
frequency,
and stroboscopy. °á°ú:Results: There were 121 eligible patients (55.4% male, age 63.7
years). VHI-10 significantly improved from 25.7 +/- 7.5 to 20.9 +/-
10.9 at 3 months (P < .001) and 19.1 +/- 11.5 at 6 months (P < .001).
MPT improved from 6.2 +/- 5.4 seconds to 9.4 +/- 7.1 seconds at 3
months (P < .001) and 11.3 +/- 8.2 seconds at 6 months (P < .001).
GRBAS improved in 74.8% of patients ((65.2, 82.8) 95% CI) at 3 months
and 80.8% ((69.9, 89.1) 95% CI) at 6 months. Stroboscopy showed a
glottic gap improvement in 74.8% of patients ((65.8, 82.4) 95% CI) at
3 months and 80.3% ((65.9, 88.5) 95% CI) at 6 months. Fundamental
frequency was unchanged, as expected. Multivariate analysis reported
that no factors were associated with better voice outcomes. Overall,
177/181 (97.8%) injections were completed with no significnat
complications. °á·Ð:Conclusion: LEVFI is an effective, novel technique to treat glottic
insufficiency with improved voice outcomes, high completion rate,
and no
significant complications |