| DEP. OF OTOLARYNGOLOGY-HEAD AND NECK SURGERY, NAGASAKI GOTO CHUOH HOSP1, DEP. OF SOCIAL EPIDEMIOLOGY, GRADUATE SCHOOL OF MEDICINE AND SCHOOL OF PUBLIC HEALTH, KYOTO UNIV2, DEP. OF GENERAL MEDICINE3, DEP. OF OTOLARYNGOLOGY-HEAD AND NECK SURGERY4, NAGASAKI UNIV. GRADUATE SCHOOL OF BIOMEDICAL SCIENCES, |
¸ñÀû: In chemoradiotherapy for head and neck squamous cell carcinoma
(HNSCC), longer waiting period for treatment adversely affect survival
outcomes. However, factors influencing treatment delays have not yet
been completely elucidated, and appropriate responses to such factors
suggest further investigation. We conducted a study to clarify factors
that lead to delays in the initiation of chemoradiotherapy for HNSCC.
In particular, we focused on the residence of patients, taking into
account the fact that our hospital's medical area includes many remote
islands. ¹æ¹ý:Medical records of patients with squamous cell carcinoma of the
oropharynx, hypopharynx, or larynx, who received radiotherapy or
chemoradiotherapy at the Department of Otolaryngology, Nagasaki
University School of Medicine were analyzed.
Cases of recurrence and cases treated at other hospitals were
excluded.
The primary outcome was the waiting period for treatment. Using the
median waiting period as the cutoff value, patients were classified
into those with a short waiting period and those with a long waiting
period. The association between the waiting period for treatment and
factors such as the patient's residence, department of first visit,
primary site, stage, receiving welfare benefits, and irradiation
method was evaluated. Statistical analysis was performed using JMP Pro
14.2.0, with uni- and multi-variate logistic regression analyses.
°á°ú:164 patients were included. Finally, 125 patients who did not meet the
predefined exclusion criteria were included in the analysis.
Uni- and multi-variate logistic regression analyses revealed that
residing in a remote area was significantly associated with longer
treatment delays (adjusted OR: 7.60, 95% CI: 1.9329.98, p < 0.01). In
addition, first visit to a non-ENT department was significantly
associated with delayed treatment (adjusted OR: 7.27, 95% CI: 2.6020.36,
p < 0.01).
°á·Ð:In this study, patient's residence and choice of department for first
visit were significantly associated with longer waiting period for
treatment. It is necessary to devise ways to reduce the impact of these
factors on the waiting period for treatment. |