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DIFFERENTIAL DIAGNOSIS BETWEEN PLEOMORPHIC ADENOMA AND CARCINOMA EX PLEOMORPHIC ADENOMA: FOCUS ON CLINICAL AND MR FINDINGS
DEP. OF OTOLARYNGOLOGY HEAD AND NECK SURGERY, JAPANESE RED CROSS SOCIETY HIMEJI HOSPITAL
ASUKA SATO, ASUKA SATO
¸ñÀû: The present study aims to evaluate clinical characteristics of CXPA and PA, and to identify factors associated with differential diagnosis of these conditions. ¹æ¹ý:We reviewed the medical records of 6 CXPA and 127 PA patients treated surgically at our institution from 2008 to 2024. °á°ú:Univariate analysis showed significant differences in factors of spontaneous pain (p = 0.044), facial nerve palsy (p = 0.045), and subjective enlargement (p < 0.01) between CXPA and PA patients. On magnetic resonance imaging (MRI) findings, proportions of masses with irregular margins, localization in deep lobe, and low levels of apparent diffusion co-efficient (ADC) were significantly higher among patients with CXPA than among those with PA (p < 0.01, p = 0.048, and p < 0.01, respectively). Multivariate analysis identified spontaneous pain and masses with irregular margins associated with CXPA (p = 0.047, p = 0.013). °á·Ð:A symptom of spontaneous pain and masses with irregular margins could be a factor suggesting CXPA rather than PA. Low levels of ADC indicated the possibility of CXPA. Regarding the difference in ADC values between CXPA and PA patients, accumulating a larger number of these cases would be necessary for more accurate analysis.


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