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Á¢¼ö¹øÈ£ - 980357 HNOP 1-2 |
ESTABLISHMENT OF A CLINICAL SCORING SYSTEM FOR THYROID MASSES |
DEPERMENT OF OTORHINOLARYNGOLOGY- HEAD AND NECK SURGERY©Ö, OSPITAL NG MAYNILA MEDICAL CENTER©÷ |
FRANZ LAURENCE LANDICHO ALVAREZ,
ALVAREZ, FRANZ LAURENCE©Ö, ALCIRA, RAMON CARMELO©÷
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¸ñÀû: General: To determine the predictive accuracy of a clinical scoring
scale based on history and physical examination distinguishing benign
and malignant thyroid mass after thyroidectomy. ¹æ¹ý:1. Study Design and Setting
This study will be an Ambispective study (54 months retrospective and 18
months prospective with reference month of July 2022) that will involve
screening and records review for patients in the outpatient department
who came in for anterior neck mass at Ospital ng Maynila andcorrelating
them with the final biopsy after thyroidectomies. °á°ú:Patient clinical and demographic characteristics will be summarized
using frequency and proportion for categorical variables and mean with
standard deviation for continuous variables. Categorical variables
will be compared between those with benign versus malignant mass using
chi-square test. Continuous variables will be compared using
independent t-test. Forward stepwise, multiple logistic regression
analyses will be done to identify significant predictors of
malignancy. Variables to be included are those which have p-value<0.10
in the univariate analysis. The scoring for the significant predictors
will be determined using the regression coefficients in the final
model. The optimum cut-off point of the clinical scoring scale and its
accuracy will be determined using Receiver Operating Curve (ROC)
analysis. Two-by-two table analysis will be created using the
cut-off point to compute for sensitivity, specificity, and predictive
values along with 95% confidence interval. A p-value<0.05 will be
considered significant and all analyses will be done using STATA14. °á·Ð:The scoring system for the variables included shows a significant
correlation except for the family history of malignancy |
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