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ESTABLISHMENT OF A CLINICAL SCORING SYSTEM FOR THYROID MASSES
DEPERMENT OF OTORHINOLARYNGOLOGY- HEAD AND NECK SURGERY©Ö, OSPITAL NG MAYNILA MEDICAL CENTER©÷
FRANZ LAURENCE LANDICHO ALVAREZ, ALVAREZ, FRANZ LAURENCE©Ö, ALCIRA, RAMON CARMELO©÷
¸ñÀû: General: To determine the predictive accuracy of a clinical scoring scale based on history and physical examination distinguishing benign and malignant thyroid mass after thyroidectomy. ¹æ¹ý:1. Study Design and Setting This study will be an Ambispective study (54 months retrospective and 18 months prospective with reference month of July 2022) that will involve screening and records review for patients in the outpatient department who came in for anterior neck mass at Ospital ng Maynila andcorrelating them with the final biopsy after thyroidectomies. °á°ú:Patient clinical and demographic characteristics will be summarized using frequency and proportion for categorical variables and mean with standard deviation for continuous variables. Categorical variables will be compared between those with benign versus malignant mass using chi-square test. Continuous variables will be compared using independent t-test. Forward stepwise, multiple logistic regression analyses will be done to identify significant predictors of malignancy. Variables to be included are those which have p-value<0.10 in the univariate analysis. The scoring for the significant predictors will be determined using the regression coefficients in the final model. The optimum cut-off point of the clinical scoring scale and its accuracy will be determined using Receiver Operating Curve (ROC) analysis. Two-by-two table analysis will be created using the cut-off point to compute for sensitivity, specificity, and predictive values along with 95% confidence interval. A p-value<0.05 will be considered significant and all analyses will be done using STATA14. °á·Ð:The scoring system for the variables included shows a significant correlation except for the family history of malignancy


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