목적: This study aims to present an institutional experience in ultrasound-guided ethanol ablation in patients with predominantly benign cystic nodules in a tertiary government hospital the Philippines. 방법:Eleven patients (10 female and 1 male) who complained of a palpable anterior neck mass between January and December of 2023 were selected and offered EA as the treatment were included in the present study. Written, informed consent was obtained from all patients prior to each EA. The mean age of the patients at the time of the initial EA treatment was 42.0 years (range: 19 to 78 years). Patients were initially assessed using portable ultrasound where nodules with a cystic component comprising greater than 50% of the total volume. The size, proportion of solid component, vascularity, and internal contents of the cystic component were carefully evaluated on US. Procedures are generally performed on an outpatient basis under complete US guidance. Real-time US was performed using high resolution ultrasound instrument. The volume of the nodule was calculated using the ellipsoid formula. Symptoms during the procedure were noted. Repeat ultrasound was done to assess the post EA measurement. Imaging surveillance after EA is usually performed at 1 to 6 months after ablation. 결과:Of the 11 patients in the study, 10 were subsequently treated with one session of EA for the predominantly cystic nodule, 1 showed significant increase in size cystic and solid nodule after 3 months post EA underwent Total thyroidectomy under general anesthesia and 1 patient lost to follow up after 1 month post EA. As observed on follow-up US (mean, 3.38 months range) after EA, 2 patients showed complete ablation of cystic nodules. 결론:Ethanol ablation should be considered as the first option for the treatment of pure cysts and predominantly cystic nodules that are not treated with simple aspiration. Unlike surgery, EA is a safe procedure that is easy to repeat, is inexpensive, can be performed easily on an outpatient basis, and has only transient side effects.