목적: To evaluate the feasibility, morbidity, and efficacy of the da Vinci Single port robot system in Tongue base reduction for the treatment of OSA. 방법:This study constitutes a prospective, single-center, single-group clinical investigation targeting patients diagnosed with moderate to severe obstructive sleep apnea (OSA) characterized by tongue-base hypertrophy and necessitating surgical intervention. For surgery, Single port robot-assisted tongue base reduction (SP TORS TBR) and expansion sphincter pharyngoplasty was performed by a single surgeon. The effectiveness of the surgical intervention was assessed through pre- and post-operative polysomnography, questionnaires, and physical examinations. To compare surgical modalities, a comparative analysis was also conducted between coblator-assisted tongue base resection (coblator TBR) and multiport robot-assisted tongue base resection(MP TORS TBR). 결과:In total, 25 patients who have completed postoperative assessment have been analyzed. All patients underwent simultaneous expansion sphincter pharyngoplasty and 10 of the total patients also underwent concurrent septoplasty. As a result of surgery, most of the PSG metrics were significantly improved. (AHI(p<0.001), 58.60 to 18.16, AI(p<0.001), 27.68 to 7.40, Epworth sleepiness scale (p<0.001), 8.9 to 5.8). The average console time of robotic surgery was 27.6 minutes, the volume of the removed tongue base was 7.1cc and the Estimated blood loss was 17.6cc. When success and failure groups were divided according to Sher's criteria (postoperative AHI<20 and AHI reduction rate ≥50%), 19 patients were classified as the success group and the success rate was 76%. This surgical success rate was notably higher than coblator TBR(45.8%) and MP TORS TBR(41.7%). In SP TBR, the primary complication directly associated with surgery was bleeding at the surgical site (tongue base). The incidence rate was 8% for the entire patient cohort, which is not significantly higher compared to the rates observed with the existing modalities. Additionally, temporary occurrences of foreign body sensation and taste changes were reported, with prompt resolution. The single-port system provides optimal visualization of the surgical field, facilitating precise reduction of tissue at targeted locations. 결론:Single port robot-assisted surgery shows excellent therapeutic results in patients with moderate to severe OSA who require tongue base resection. This safe and effective innovative surgical alternative holds the potential to benefit both the patient and the surgeon.