| 발표형식 : 포스터(전시)
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접수번호 - 980290 RHPX-10 |
| PERIODONTITIS IS ASSOCIATED WITH THE DEVELOPMENT OF FUNGAL SINUSITIS:A
NATIONWIDE 12-YEAR FOLLOW-UP STUDY |
| 1DEPARTMENT OF PHARMACOLOGY, JEONBUK NATIONAL UNIVERSITY MEDICAL SCHOOL, JEONJU, REPUBLIC OF KOREA2RESEARCH INSTITUTE OF CLINICAL MEDICINE OF JEONBUK NATIONAL UNIVERSITY–BIOMEDICAL RESEARCH INSTITUTE OF JEONBUK NATIONAL UNIVERSITY HOSPITAL,JEONJU, REPUBLIC OF KOREA3DEPARTMENT OF MEDICAL INFORMATICS, JEONBUK NATIONAL UNIVERSITY MEDICAL SCHOOL, JEONJU, REPUBLIC OF KOREA4DEPARTMENT OF OTORHINOLARYNGOLOGY-HEAD AND NECK SURGERY, JEONBUK NATIONAL UNIVERSITY MEDICAL SCHOOL, JEONJU, REPUBLIC OF KOREA5DEPARTMENT OF STATISTICS (INSTITUTE OF APPLIED STATISTICS), JEONBUK NATIONAL UNIVERSITY, JEONJU, REPUBLIC OF KOREA6DOCTORS DENTAL CLINIC, GUNSAN, REPUBLIC OF KOREA7SAE BOM DENTAL CLINIC, JEONJU, REPUBLIC OF KOREA8DEPARTMENT OF FORENSIC MEDICINE, JEONBUK NATIONAL UNIVERSITY MEDICAL SCHOOL, JEONJU, REPUBLIC OF KOREA9DEPARTMENT OF OTORHINOLARYNGOLOGY-HEAD AND NECK SURGERY, CHA BUNDANG MEDICAL CENTER, CHA UNIVERSITY SCHOOL OF MEDICINE, BUNDANG, REPUBLIC OF KOREA |
| SOLA HAN,
MIN GUL KIM¹ ², MIN GU KANG³ ⁴, MIN GYU LEE³ ⁴, SEONG J YANG⁵, SANG WOO YEOM³ ⁴, JONG HWAN LEE⁴, SANG MOON CHOI⁶, JI HYUN YOON⁷, EUN JUNG LEE² ⁴, SANG JAE NOH² ⁸, MIN-SU KIM⁹, JONG SEUNG KIM² ³ ⁴
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목적: invasive fungal sinusitis, periodontitis, sinonasal fungal ball 방법:The periodontitis group was randomly selected from theNational Health
Insurance Service database. The non-periodontitis group was obtainedby
propensity score matching considering several variables. The primary end
point wasthe diagnosis of sinonasal fungal balls (SFBs) and invasive
fungal sinusitis (IFS). 결과:The periodontitis and non-periodontitis groups included 12,442 and
12,442individuals, respectively. The overall adjusted hazard ratio
(aHR) for SFBs in the peri-odontitis group was 1.46 (p=.002). In
subgroup analysis, the aHR for SFBs was 1.59(p=0.008) for those with
underlying chronic kidney disease (CKD), 1.58 (p=.022)for those with
underlying atopic dermatitis, 1.48 (p=.019) for those with
chronicobstructive pulmonary disease (COPD), and 1.36 (p=.030) for
those with diabetesmellitus (DM), but these values are applicable only
when considering the relationshipbetween periodontitis and SFB. The
aHR for IFS in the periodontitis group was higherthan in the non-
periodontitis group (2.80;p=.004). 결론:The risk of SFBs and IFS increased after diagnosis of periodontitis.
Thistrend is often more severe in patients with DM, COPD, or CKD, but
this associationwith underlying diseases is applicable only when
considering the association betweenperiodontitis and fungal sinusitis |
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