DEPARTMENT OF OTORHINOLARYNGOLOGY-HEAD AND NECK SURGERY, UIJEONGBU ST. MARY'S HOSPITAL, COLLEGE OF MEDICINE, THE CATHOLIC UNIVERSITY OF KOREA©ö, DEPARTMENT OF OTORHINOLARYNGOLOGY-HEAD AND NECK SURGERY, INCHEON ST. MARY'S HOSPITAL, COLLEGE OF MEDICINE, THE CATHOLIC UNIVERSITY OF KOREA©÷ |
¸ñÀû: Previous research has explored the effect of nasal congestion on the
emergence and exacerbation of obstructive sleep apnea (OSA) but
yielded diverse analysis methodologies and outcomes. Some prior
studies have identified that the major nasal inspiratory resistance is
located at the anterior portion of the inferior turbinates. Our study
focuses on evaluating the influence of the nasal cross-sectional area
(CSA) on OSA at this specific site, utilizing both acoustic rhinometry
(AR) and computed tomography (CT) coronal view. ¹æ¹ý:Medical records of patients who underwent polysomnography, paranasal
sinus CT, and AR were extracted between December 2018 and December 2022.
We excluded individuals below 18 years of age and those lacking physical
measurement data. Participants were categorized into mild to severe OSA
and non-OSA groups based on their apnea-hypopnea index (< or ¡Ã 5/hour),
and the clinical characteristics were compared between the groups. We
also analyzed moderate to severe OSA cases against others and severe OSA
against others. Furthermore, correlation analysis was performed between
the continuous variables. °á°ú:Finally, 308 patients were enrolled in the study. Compared to the non-
OSA group, those with mild to severe OSA showed a higher prevalence of
males, older age, and higher BMI (p = 0.004, 0.001, and 0.022). Nasal
CSA measurements by AR and CT did not differ significantly across
groups, yet binomial logistic regression indicated that sex, age, BMI,
and AR-measured nasal CSA significantly impacted OSA (p = 0.004,
<0.001, 0.036, and 0.050, respectively). The minimum value between
right and left CSAs measured by AR was inversely related to OSA
likelihood, particularly in non-obese individuals, as evidenced by
logistic regression analysis (p = 0.015). This association was not
observed in obese patients. When comparing moderate to severe OSA
cases with the others and when comparing severe OSA cases with the
others, no significant CSA differences were found, even after
adjusting for confounding factors. In correlation analysis, AR-
measured CSA negatively correlated with the apnea-hypopnea and
obstructive apnea-hypopnea indexes (p = 0.048 and 0.046), though these
correlations lost significance when controlling for BMI and age. °á·Ð:Nasal CSA at the inferior turbinate anterior head level, along with
sex, age, and BMI, significantly influences OSA development. Before
adjusting confounders, the absence of significant CSA differences
might be attributed to age-related CSA increase due to atrophic
changes. The association between CSA and OSA might be obscured in
obese patients by more pronounced oropharyngeal narrowing. CT-measured
CSA showed no significant correlation with OSA, unlike AR
measurements. Further understanding of the nasal CSA-OSA relationship
could be crucial in enhancing preventive and therapeutic strategies
for OSA in patients with nasal obstruction. |