목적: The role of Fractional Exhaled Nitric Oxide (FeNO) has been established in asthma management, yet its effectiveness in forecasting the reccurrence of chronic rhinosinusitis with nasal polyps (CRSwNP) is still under investigation. 방법:This retrospective cohort study was conducted at a tertiary medical center. It included 30 patients with a diagnosis of CRSwNP who underwent functional endoscopic sinus surgery. Nasal polyp recurrence was determined through endoscopic observation. Data on FeNO levels, Lund- Mackay CT scores, recurrence timing, total monitoring duration, and treatments post-recurrence were collected and analyzed. 결과:The study established a FeNO level of 75 parts per billion (ppb) as a predictive marker for CRSwNP recurrence, based on the receiver operating characteristic curve analysis (sensitivity: 60.0%, specificity: 76.0%, area under curve [AUC]: 0.608; 95% CI: 0.289–0.927). Kaplan-Meier survival analysis suggested a higher and earlier recurrence in patients with elevated FeNO levels, although this was not statistically significant (P=0.151). Importantly, there was a significant correlation between higher FeNO levels and increased Lund-Mackay scores, particularly in the anterior and posterior ethmoid sinuses, osteomeatal complex, and olfactory cleft. 결론:FeNO levels above 75ppb are indicative of a greater probability of CRSwNP recurrence and more severe disease, as shown by higher Lund- Mackay scores in CT scans. These findings highlight the potential of FeNO as a predictive biomarker in CRSwNP management.