목적: The management of almost all salivary gland neoplasm is surgical excision. So, a pre-operative diagnosis of salivary neoplasm assists the clinician planning the need for operation or extent of surgery. FNAC is a popular tool for diagnosis of salivary gland neoplasm due to its easy accessibility for the procedure. Despite of increased complication risk, such as hemorrhage, facial nerve injury, and tumor-seeding, Core needle biopsy is outstanding diagnostic tool compared to FNAC for high sensitivity , high specificity and low possibility of inadequate samples. The purpose of this study is to compare sensitivity, specificity and diagnostic accuracy of FNAC with those of core needle biopsy. 방법:This study included 171 patients who underwent pre-operative FNAC or core needle biopsy followed by surgical procedure and histological examination. FANC and core needle biopsy diagnosis compared with the final histologic diagnosis. Sensitivity, specificity and diagnostic accuracy ware calculated. 결과:Of the 171 patients, 116 cases underwent core needle biopsy and 66 cases underwent FNAC, and 11 cases underwent both procedures. 152 patients among the 171 patients were diagnosed benign neoplasms(pleomorphic adenoma 100, warthin 44, other 8), 19 patients were diagnosed malignant neoplasm. 10 malignat neoplasms were diagnosed for malignancy correctly by Core needle biopsy and 1 malignancy was misdiagnosed. 4 malignant neoplasms were diagnosed for malignancy correctly by FNAC and 3 malignancy were misdiagnosed. 결론:Although FNAC is a diagnostic tool that can be assessed easily in salivary neoplasm work-ups, it showed lower diagnostic accuracy compared to Core needle biopsy in malignant neoplasm of a salivary gland work-ups. Clinicians should apply relative advantage of each techniques properly.