목적: We investigated the predictive role of volumetric parameters measured from Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F18-FDG PET/CT) in patients with malignancy of nasal cavity and paranasal sinus. 방법:39 patients with malignancy of nasal cavity (n=16) and paranasal sinus (n=23) who underwent PET/CT prior to treatment were enrolled. A volume of interest was placed on PET/CT images covering the entire tumor volume. The maximum standardized uptake value (SUVmax) and volumetric parameters were measured using thresholds of both SUV2.5 and 40% of SUVmax metabolic tumor volume (MTV2.5, MTV40) and total lesion glycolysis (TLG2.5, TLG40). Recurrence free survival and overall survival was defined as the time from the diagnosis to recurrence and death. 결과:Median values of MTV2.5, TLG2.5, MTV40, and TLG40 were 51.9, 237.0, 15.48, and 99.0 respectively. SUVmax (p=0.0030), SUVmean2.5 (p=0.0488), and SUVmean40 (p=0.0130) were higher in patients with nodal metastasis. In univariate analysis, MTV40 was the only significant factor that predicts the overall survival (hazard ratio 7.09 1.39-36.03, p=0.03). However, none of PET parameters (SUVmax, SUVmean2.5, MTV2.5, TLG2.5, SUVmean40, MTV40, TLG40) were significant predictors of recurrence. 결론:Although the MTV cannot predict recurrence, the MTV could be prognostic values associated with overall survival of patients with malignancy of nasal cavity and paranasal sinus.