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Comparison of Interpretation Methods in Allergic Skin Test
Dept. of Otorhinolaryngology Head & Neck Surgery, Kyung Hee Univ., School of Medicine
Sung-hwa DONG, Sung-hwa DONG, Su-jin KIM, Kun-hee LEE, Joong-saeng JO, Sung-wan KIM
¸ñÀû: Allergic skin test is a commonly used test to evaluate an immediate immune response either by skin prick test (SPT) or intradermal test. SPT is widely used Several methods have been proposed to interpret SPT. However, there has been no comparison study about inter-test relationship. The aim of this study compare three different interpreting methods and define the relationship among them. ¹æ¹ý:We examined SPT to 370 patients who visited allergy clinic complaining of nasal symptoms from January to December 2014.Three different interpreting methods were used for defining positivity in SPT such as interpretation by comparing wheal sizes of allergen and histamine , the biggest diameter of the wheal size more than 3 mm , and the biggest diameter of the erythema greater than 15 mm. And we compared the positivity among 3 different interpretation methods. The validity of each interpreting method was evaluated by comparing positivity to TNSS. °á°ú:Positivity in SPT were reported as 49.6% in A/H ratio method, 63.3% in Wheal size method, and 60.4% in Erythema size method, respectively.Subjects who showed negative result in A/H ratio method have positive results in Wheal size method or Erythema size method were 15.1% and 12.9%, respectively.Subjects showing negative result in A/H ratio but positive result in Erythema size method had significantly higher itching, sneezing, and TNSS than subjects showing both negative results. But, Subjects showing negative result in A/H ratio but positive result in Wheal size method had significantly higher rhinorrhea, nasal obstruction and TNSS than subjects showing both negative results. °á·Ð:TNSS score was higher in subjects showing negative result in A/H ratio but positive result in Wheal size method and Erythema size method than subjects showing both negative results.Thus diagnosing allergic rhinitis patients, we may consider Wheal size method and Erythema size method as additional tools to assist A/H ratio method.


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