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High Signal on FLAIR, a Predictable Factor for Progression to Menieres Disease in Low Tone Loss Patients
Dept. of Otorhinolaryngology, Univ. of Ulsan College of Medicine, Asan Medical Center
Sang Hun LEE, Jung Ho AHN
¸ñÀû: Three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) image in MRI has recently been developed to detect high concentrations of protein or hemorrhage. Other article have previously reported that 50% of patients with sudden hearing loss show high signals in the affected inner ear on 3D-FLAIR MRI. However, the relationship between 3D-FLAIR findings and hearing prognosis is unclear. Our objective was to evaluate the relationship between the results of 3D-FLAIR MRI at 3 Tesla and prognosis (especially progression to Menieres disease) in sudden hearing loss. ¹æ¹ý:Retrospective study in a tertiary referral center with a clinical data of 79 patients diagnosed as having unilateral sudden hearing loss from January 2014 to December 2014. The low-tone loss type meets the following criteria the average hearing level at 250, 500 and 1 kHz Hz is at least 10 dB worse than that at 2, 4, and 8 kHz. 8 patients were categorized as low tone loss. The rates of progression to Meniere's disease for patients with low-tone loss type were compared with those for other sudden hearing loss. °á°ú:The median age at diagnosis was 46.8 (range 5 to 79 years). 49 (62%) of patients were left ear sudden hearing loss and the others were right ear. Pearson Chi square test indicated that low tone loss and Menieres disease had statistically significant correlation. (p=0.003, correlation coefficient=0.335) But the correlation between high signal intensity in FLAIR and Menieres disease had not statistical significance. (p=0.378) °á·Ð:The association with low tone loss and Menieres disease has been confirmed. But the correlation between high signal intensity in FLAIR and Menieres disease had not statistical significance. The lack of number of cases is possible cause of the result.


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