목적: Ohngrens line is a line that connects the medial canthus of the eye to the angle of the mandible. Lesions occurring superior or posterior to this imaginary line have been thought to be associated with a poor prognosis because of the proximity of the orbit, the pterygopalatine and infratemporal fossa. The aim of this study was to evaluate whether the Ohngrens line can be used as a prognostic factor in maxillary squamous cell carcinoma or not 방법:A retrospective study was conducted with 43 patients who received maxillectomy for T2-T4 maxillary squamous cell carcinoma. We compared the MRI findings of 18 structures around the maxillary sinus with those of intra-operative or post-operative pathologic findings and divided the extensions of maxillary squamous cell carcinoma into five directions superior, medial, inferior, anterior and posterolateral. Also we tried to find out whether superior-posterior extension above Ohngrens line has poor prognosis when compared to an anterior-inferior extension 결과:5-year overall survival rate was 60% and 5-year disease specific survival rate was 78%. Among 43 cases, superior extensions were found in 11 cases(25%), inferior in 16 cases(37%), medial in 22cases(51%), anterior in 11 cases(25%) and posterolateral extensions in 21 cases(49%). When using Kaplan-Meier survival analysis, only medial extensions had statistically significant poor survival rate when compared to other directions(p<0.05) 결론:In conclusion, Ohngrens line didnt show any predictive value in prognosis of maxillary squamous cell carcinoma after surgical treatment. Accurate preoperative evaluation and complete surgical resection for superior posterior extension showed comparable oncologic results when compared to anterior inferior extension below Ohngrens line. Medial extension not infrequently can cause brain invasion through ethmoid sinus and it might be the reason of poor prognosis of medial extension in maxillary squamous cell carcinoma