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Á¢¼ö¹øÈ£ - 890365 RHOP-45 |
Changes in Skin Sensitivity to Inhalant Allergens over 3 Years in
School-
Aged Children |
Dept. of Otorhinolaryngology, Seoul National Univ. College of Medicine1 |
Jae Hyun LIM,
Jae Hyun LIM1, Yoon-Seok CHOI1, Seung No HONG1, Doo Hee HAN1, ARCO-kids study group, Chae-Seo RHEE1
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¸ñÀû: Determining the allergen is important for the diagnosis and
management of
allergic diseases. The skin prick test (SPT) has been widely used
to
identify allergens. Skin sensitivity to allergens can change due
to
changes
in lifestyle and outdoor environments. Little is known about the
changes of
allergen sensitivity in young children. ¹æ¹ý:In this Allergic Rhinitis Cohort Study for Kids (ARCO-kids),
consecutive
pediatric patients with rhinitis symptoms underwent skin prick
tests
(SPTs).
1689 children were assessed for allergen sensitivity from 2009 to
2011. SPTs
were performed with inhalant allergens at initial survey and re-
performed at
3-year follow-up survey. °á°ú:280 children fulfilled the follow-up SPT. Initially 72 children were
negative for SPT and 25 (34.7%) developed skin sensitivity during the 3-year
study. Among 25 children, 20 (80%) were newly sensitized to house dust mites
(HDM). 194 (69.3%) were sensitized to house dust mites (HDM) at initial
survey and 213 (76.1%) were sensitized to HDM at follow-up survey. Skin
sensitivity to cat, dog, tree, grass, fungus also increased during the
study. 102 children were sensitized only to HDM. After 3-year follow up, 41
(40.2%) were newly sensitized to other antigens such as cat, dog, trees. °á·Ð:Our study showed the changes in skin sensitivity to inhalant
allergens over
3 years in school-aged children. Skin sensitivity was increased
in
both non-
sensitizer and mono-sensitizer to HDM. |
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