¸ñÀû: LASER cordectomy in early glottic cancer could be a good option for early glottis cancer and 5-year local control rate was reported from 76% to 100%. But we sometimes encounter local recurrence after few years disease free interval. So we designed this study to figure out the risk factor that is related to the late recurrence in early glottis cancer. ¹æ¹ý:A retrospective review of the medical record of the patients who were
diagnosed with glottis cancer and had LASER cordectomy in T1 ,T2 stage
from 2000 to 2010. 138 patients enrolled to this study and we classified
these patient to three group(no recurrence group/early recurrence group
within 2 years/late recurrence group after 2yrs). We investigate age,
sex, smoking history, pre-op imaging, pre-op physical findings, post-op
pathology and local recurrence. °á°ú:In 138 patients 18 patients(13%) showed local recurrence, and 12
patients recurred within 2 years following surgery, 6 patients
recurred after 2 years following sugery. In early recurrence group,
we found more frequent paraglottic space invasion in pre-op imaging
and ant. commissure involvement in physical examination than non-
recurrence group(33.3% vs 10.5% with pre-op imaging paraglottic
invation/ 57.3% vs 18.3% with ant. commissure involvement). In late
recurrence group, all 6 patients had salvage laryngectomy and all the
patients showed ant. commissure invasion pre-operatively in physical
examination. Interestingly, 4 patients out 6 in late recurrence group
were current smoker after surgery and it had stastical impact(p-
value=0.04) °á·Ð:In early glottis cancer, local recurrence could be occured
occasionally after few years of disease free period. From the result
of our study, we concluded that paraglottic space and ant. commissure
involvement would be the risk factor for early or late recurrence,
repectively. So we should closely review the pre-op imaging and
physical finding to decreased the local recurrence in early glottis
cancer. |