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Risk Factor for Local Recurrence in Early Glottic Cancer: Long-Term Result
Dept. of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic Univ. of Korea
Sang-Yeon KIM, Sang-Yeon KIM, Kwang-Jae CHO, Young-Hoon JOO, In-Chul NAM, Min-Sik KIM
¸ñÀû: LASER cordectomy in early glottic cancer could be a good option for early glottis cancer and 5-year local control rate was reported from 76% to 100%. But we sometimes encounter local recurrence after few years disease free interval. So we designed this study to figure out the risk factor that is related to the late recurrence in early glottis cancer. ¹æ¹ý:A retrospective review of the medical record of the patients who were diagnosed with glottis cancer and had LASER cordectomy in T1 ,T2 stage from 2000 to 2010. 138 patients enrolled to this study and we classified these patient to three group(no recurrence group/early recurrence group within 2 years/late recurrence group after 2yrs). We investigate age, sex, smoking history, pre-op imaging, pre-op physical findings, post-op pathology and local recurrence. °á°ú:In 138 patients 18 patients(13%) showed local recurrence, and 12 patients recurred within 2 years following surgery, 6 patients recurred after 2 years following sugery. In early recurrence group, we found more frequent paraglottic space invasion in pre-op imaging and ant. commissure involvement in physical examination than non- recurrence group(33.3% vs 10.5% with pre-op imaging paraglottic invation/ 57.3% vs 18.3% with ant. commissure involvement). In late recurrence group, all 6 patients had salvage laryngectomy and all the patients showed ant. commissure invasion pre-operatively in physical examination. Interestingly, 4 patients out 6 in late recurrence group were current smoker after surgery and it had stastical impact(p- value=0.04) °á·Ð:In early glottis cancer, local recurrence could be occured occasionally after few years of disease free period. From the result of our study, we concluded that paraglottic space and ant. commissure involvement would be the risk factor for early or late recurrence, repectively. So we should closely review the pre-op imaging and physical finding to decreased the local recurrence in early glottis cancer.


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