목적: Nasopharyngeal carcinoma (NPC) is rare in young patients. The aim of this study is to analyze the clinical features, treatment outcome in patients younger than 20 years old at our institution 방법:Twenty three young NPC patients managed by chemotherapy(CT) and radiotherapy (RT) were identified from a database of Asan Medical Center from 1990 to 2012. Demographic, pathological, and outcomes data were analyzed. 결과:Twenty patients were men and 3 were women. The median age at diagnosis was 17 (range, 12-20) years. The most common presenting symptom was neck mass (60.9%, 14/23). Twenty-one patients had stage III-IV, and two had a stage II lesion. Most patients (87%, 20/23) received combination of cisplatin-based CT and RT, 2 patients received RT only, 1 patient had CT only due to distant metastasis initially. There were complication with xerostomia, velopharyngeal insufficiency, hypothyroidism and otitis media. With a median follow-up of 85 (range, 28-276) months, only 1 patients (4%) developed local recurrence , 3 patients (13%) developed distant metastases within 16 months after treatment. 5-year overall survival (OS), 5-year disease-free survival (DFS) were 84.8% and 81.8%, respectively. Patients aged 17 years had better OS, DFS compared to aged >17 years (P =0.028 and P=0.008, respectively). Tumor stage, gender, and RT dose were not significantly related with survival outcome. 결론:Although survival outcome in young NPC patients was better than adult patient, distant metastasis remains a major obstacle for the cure of NPC in the young population. Multidisciplinary effort are needed to improve the survival and quality of life.