Bisphosphonate reduced the activity of osteoclast result in suppression
of bone resorption. Since 1960s, bisphosphonate was used in treatment of
many bone metabolic disorders. After 2003, the necrosis of jaw was
reported as long term side effect of bisphosphonate called as
BRONS(bisphosphonate-related osteonecrosis of the jaw).
84-years old female visited in otorhinolaryngology clinic. She has both
nasal obstruction and watery rhinorrhea since several months ago. In
physical examination, mucosal swelling of right inferior meatus and
accompanied pus collection were seen. She has history of long term use
of bisphosphonate over 10 years for treatment of osteoporosis, since her
right hip joint was fractured.
In general anesthesia, we operated both endoscopic sinus surgery,
debridement of necrotic bone, extraction of two molar teeth. After
surgery, the patient follow up with our clinic and endocrinology clinic,
stopped in bisphosphonate and continued with calcium/cholecalciferol
combination. Until post-operation 1 month, there is no complication.
We reported this case for BRONJ with maxillary sinusitis and post-
operation management.
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