목적: Oral discomfort and laryngopharyngeal reflux (LPR) are often associated with obstructive sleep apnea syndrom(OSAS). This study aims to evaluate whether these symptoms change after multilevel surgery (MLS) for OSAS. 방법:The patients who underwent MLS for OSAS from April 3, 2009 to September 13, 2014 were enrolled in this study. Sleep study, physical examination, CT and cephalometry were done at initial visit. All patients were asked to fill up RSI after MLS. 결과:Seventy-eight of 86 patients (74 males and 12 females) who completed initial questionnaire were enrolled in this study. Eight patients refused to be enrolled and excluded. Mean ages and BMI are 42.811.7 years 26.63.0 respectively. Mean apnea-hypopnea index (AHI) was 29.916.2/hr. Mean preoperative & postoperative RSI were 12.28.5 and 5.36.8 respectively with statistically significant change (P<0.001). Thirty-two out of 86 patients (38%) had RSI more than 12 who were considered positive for LPR before the surgery. However, 22 of these patients (60%) showed improvement more than 50% after the surgery. Of the specific variables, heart burn (chest pain) showed most dramatic improvement (69%) followed by throat clearing (57%), and postnasal drip (52%). 결론:LPR is common in patients with OSAS and might improve after multilevel surgery for OSAS. Further objective study is needed to investigate the effect of sleep surgery for LPR