목적: To analyze and compare the role of local anesthesia with placebo in flexible nasopharyngolaryngoscopy. 방법:A prospective, longitudinal and analytical study conducted among 84 patients required flexible nasopharyngolaryngoscopy dividing in two groups of 4% xylocaine and normal saline spray each. The questionnaires about nasal pain, throat discomfort, bad taste, feeling of nausea and overall discomfort were filled up by using numeric rating scale. Data was analyzed using SPSS 11.5 software. 결과:Regarding the nasal pain, throat pain, feeling of nausea and overall discomfort, they were statistically not significant in both groups. Whereas the bad taste score was less in normal saline spray group as compared to 4% xylocaine spray group showing statistically significant (p=0.000). 결론:Though we do use topical local anesthesia frequently for the flexible nasopharyngolaryngoscopy, there is no such extra benefit as compared to normal saline spray.