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Candida Species in Tobacco Chewers and Non-Chewers - A Comparative Study
Dept. of Oral Pathology and Microbiology1,Sri Dharmasthala Manjunatheshwara College of Dental Sciences and Hosp., Dharwad, Karnataka, India, Dept. of Oral Pathology2,Indira Gandhi Institute of Dental Sciences, Pillaiyar Kupam, Pondicherry, Dept. of Oral & Maxillofacial Pathology and Microbiology3,Hitkarini Dental College & Hosp., Jabalpur, India, Karnataka Cancer Treatment and Research Institute4,Hubli, Karnataka, India, Dept. of of Microbiology5,Maratha Mandals Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belgaum, Karnataka, India, Karnataka Univ.6,Dharwad, Karnataka, India
Arunee GARG, Arunee GARG1, Amsavardani TAYAAR S2, Rashmi BANGERA1, Sonalika G. WANJARI3 , B.R. PATIL4, Kishore G. BHAT5, M.V. MUDDAPUR6
¸ñÀû: Worldwide tobacco consumption is the most important risk factor for Oral squamous cell carcinoma (OSCC). Candida albicans (CA) is a commonly isolated commensal in the oral cavity and has been suggested to play a role in oral carcinogenesis. We attempted to study the variation in Candida both qualitatively and quantitatively in tobacco chewers (C) and non-chewers (NC) with the former being the prime group amongst South - East Asians who are inflicted by OSCC. ¹æ¹ý:Frequency of isolation (FOI), mean colony forming units (mCFU) and speciation of Candida were done using whole unstimulated saliva samples from sixty one NC and fifty three C. The data was subjected to appropriate statistical analysis using SPSS 20 for Windows. °á°ú:The isolation frequency and colonisation was less in C compared to NC but the difference was insignificant. Both CA and non Candida albicans Candida species (NCACS) were isolated in the study groups. °á·Ð:The quantitative changes induced in Candida carriage and isolation were not significant among C and NC but the species isolated seemed to be considerably influenced by the habit of chewing tobacco according to us.


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