목적: The aim of this study was to investigate the relationship between hearing loss and tinnitus and health-related quality of life (HRQoL) in South Korea using data from the Korea National Health and Nutrition Examination Surveys (KNHANES) during 2010-2012. 방법:Cross-sectional data of 11,266 adults who completed the KNHANES were analysed. According to the hearing loss and tinnitus, the subjects were divided into four groups as follows normal hearing without tinnitus, normal hearing with tinnitus, hearing loss without tinnitus, and hearing loss with tinnitus group. 결과:Among the population 19 years of age, the prevalence of unilateral hearing loss was 9.69% and that of tinnitus in the prior 12 months was 32.76%. The hearing loss with tinnitus group had the highest percentage of subjects who responded some or extreme problems in all five dimensions (mobility, self-care, usual activities, pain/discomfort, and anxiety/depression) of HRQoL. After adjustment for age, gender, body mass index, smoking status, alcohol intake, regular exercise, house income, education level, diabetes, hypertension, and stress level, the odds ratio (OR) was 1.47 (95% CI, 1.07-2.02) for mobility, 1.38 (95% CI, 0.86-2.23) for self-care, 1.59 (95% CI, 1.07-2.37) for usual activity, 1.28 (95% CI, 0.96-1.71) pain/discomfort, and 1.84 (95% CI, 1.25-2.70) anxiety/depression of HRQoL in the hearing loss with tinnitus group, compared with the normal hearing without tinnitus group. The ORs for normal hearing with tinnitus group compared with hearing loss without tinnitus group was increased in all five dimensions of HRQoL after adjustment for confounders. 결론:Hearing loss with tinnitus has a considerable impact on HRQoL in Korean population. Hearing loss without tinnitus group showed better HRQoL compared than normal hearing with tinnitus group.