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Comparison of the Effect of Endoscopic Sinus Surgery Versus Medical Therapy on Olfaction in Nasal Polyposis
Otorhinolaryngology research center, Dept. of Otolaryngology Head &Neck Surgery, Shahid Sadoughi Univ. of Medical Sciences,Yazd,Iran1,Dept. of Otolaryngology Head&Neck Surgery, Ilam Univ. of Medical Sciences,Ilam,Iran2,Dept. of Otolaryngology Head & Neck surgery of ShIiraz Univ. of Medical Sciences , shiraz, Iran3
Mohammad reza VAHIDI, Mohammad Hossein BARADARANFAR1, Zeynab Sadat AHMADI 1, Mohammad Hossein DADGARNIA1,Mohammad Reza VAHIDI1,Mohsen FANI1,Ali MORADI1,Abbas MIRVAKILI1,Safarali amiri ANDI2,Mohammad FARAMARZ3
¸ñÀû: Chronic rhinosinusitis is a common inflammatory condition in western countries. Nasal polyposis has different symptoms such as nasal obstruction, anterior or posterior nasal drip, reduced sense of smell, and facial pain. Medical and endoscopic Treatments are the two Main treatments for nasal polyposis. Our aim was to compare the efficacy of different methods on Olfactory function ¹æ¹ý:This non-randomized clinical study was done on 60 patients who were divided into two groups. Patients were matched based on age, history of smoking, and the severity of obstruction. The score of Lund-Mackay staging system was used to match patients in two arms of the trial based on the severity of nasal obstruction. Patients in surgery groups underwent functional endoscopic sinus surgery and then received Fluticasone propionate nasal spray for 8 weeks (400 mcg bd).Patients in the medical group were only prescribed with Fluticasone propionate with the same duration and same dose as mentioned °á°ú:As a result of treatment protocol, both medical and surgical group experienced improvement in olfactory function but statistical analyses revealed that surgery resulted in better resolution of symptoms °á·Ð:Our observation revealed that combined treatment had a better effect than medical treatment in restoring olfaction in patients with nasal polyposis.


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