목적: Nasal inverted papilloma (IP) is a benign tumor with high recurrence rates. Evidence of inflammation has been reported in IP in Caucasian studies. This study aims to investigate the histopathological patterns and their associations with clinical characteristics in Chinese patients with IP. 방법:IP tissues were obtained from 50 Chinese patients with unilateral IPs. Biopsies of inferior turbinate mucosa from 17 healthy subjects were used as controls. The histological patterns and severity of epithelial remodeling and inflammatory cell infiltration were evaluated and analyzed for associations with clinical characteristics. 결과:31% of IP specimens were classified as Grade I (mild remodeling) and 49% as Grade II (moderate and severe remodeling). Concomitant inflammatory nasal polyps were found in 14 patients (28%). Recurrent IP was strongly associated with Grade II(OR=5.81, 95% CI 1.34-25.18). Except CD4+ T cells, quantities of neutrophils, macrophages, eosinophils, CD8+ T cells, and FoxP3+ T-reg cells were significantly elevated in IP. Of these, neutrophils were the predominant cell type in IP. 결론:IPs from Chinese patients displays inflammation with prominent neutrophilia. The majority of IP demonstrated moderate to severe epithelial remodeling, which were associated with recurrent IP.