Relapsing polychondritis (RP) is a rare systemic disease characterized by recurrent, widespread chondritis of the auricular, nasal, and tracheal cartilages. Although the cause remains unknown, the etiology is suspected to be autoimmune. We describe a case of a 45-year-old man with a four-month history of bilateral auricular, and thereafter subsequently hump nose by nasal chondritis, bilateral vocal cord palsy. Infectious and neoplastic diseases were excluded by imaging and laboratory examinations. RP was diagnosed based on three McAdam's criteria. The patient was medicated with oral prednisolone with positive clinical response. In this case clinical history and detailed physical examination were fundamental in concluding the correct diagnosis and administrating the appropriate medication.