목적: Vestibular neuritis (VN) is a sudden unilateral vestibular failure. Recently, right hemispheric parietal operculum 2 (area OP2) has been suggested as core region for vestibular processing observed by the meta-analysis. In this study, we used resting state (RS-) fMRI to examine change in functional connectivity for central compensation with functional recovery in unilateral VN patients. 방법:Sixteen patients (MF = 97 mean age of 43.7 16.8) who were diagnosed as unilateral VN were included in this study (leftright = 79). Brain MRI(T1 and RS-fMRI) and clinical observation were performed within 2 days of diagnosis of acute VN and repeated at 2-3 months later (follow-up). Caloric test was performed and Korean version of the dizziness handicap Inventory (K-DHI) was collected at the time of MR imaging. Functional MR data was preprocessed with SPM12 software and seed- based analysis was performed to identify changes of RS- functional connectivity during recovery period using REST toolbox. Area OP2 in the right and the left hemispheres were selected as seed ROIs. Statistical threshold was set at p < 0.05 (FDR-corrected) 결과:We observed significantly increased connectivity with LOP2 after 3 months in vestibular network including the bilateral cingulate cortex, the right cerebellum, the right superior temporal gyrus (STG), the right OP3, the right precentral gyrus, the left insula and the visual cortices. K-DHI improvement was positively correlated with connectivity increase in the right STG, the right OP3, the right anterior cingulate gyrus and the middle cingulate gyrus. 결론:The observed function connectivity alterations to networks of the fronto-temporal, visual, and cingulate cortex for LOP2 might be related to the disturbed connectivity to ROP2 due to acute peripheral vestibulopathy, leading to central compensation of functional recovery during the first 3 months after disease onset.