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Pediatric Follicular Lymphoma in Good Prognosis with a Watch and Wait Strategy after Complete Resection a Case Report
Dept. of Otorhinolaryngology-Head Neck Surgery, CHA Bundang Medical Center, CHA Univ.
So-Yoon LEE, So-Yoon LEE, Ji Yoon KIM, Chan Ki YOO
Follicular lymphoma(FL) rarely occurs in children and adolescents (<2% of cases). FL is recognized as a unique histopathological entity in the pediatric group, with a high proportion, having grade 3, and no BCL2-rearrangement. Moreover, while most adult patients present with disseminated disease at initial diagnosis, children usually present with localized disease confined to the peripheral lymph node only. Optical treatment of pediatric FL has not yet been defined, and therapeutic strategies differ considerably with some groups applying intensive B cell NHL-type chemotherapy and others favoring a ¡°watch and wait¡±strategy after complete resection for at least BCL2-negative pediatric FL. Regardless of the type of therapy, cure rates approach 90%. A 17-year-old boy visited our hospital complaining with sub-mental neck mass. Irregular round-shaped mass was 3.5x2.5x2 cm in size with well encapsulated. Excisional biopsy was performed and the result reported as pediatric FL with BCL-2 negative. There was no evidence of distant disseminated lesion. Stage I (grade 3) pediatric FL had planned to watch and wait¡±strategy. We report our case with review of literatures.


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