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Association between Hearing Impairment and Chronic Kidney Disease: A Cross-Sectional Study of the Korean General Population
Dept. of Otorhinolaryngology1 and Occupational and Environmental Medicine2, Yonsei Univ., Wonju College of Medicine, Wonju, Korea
Young Joon SEO, Young Joon SEO1, Tae Hyung HA1, Sang Baek KO2, Sang Yoo PARK1
¸ñÀû: We aimed to evaluate the association between hearing level and the prevalence of chronic kidney disease (CKD) in the largest population based cross- sectional study to date. ¹æ¹ý:This cross-sectional study was based on the Korean National Health and Nutritional Examination Survey (KNHANES). It included 5,275 participants ¡Ã19 years of age whose estimated glomerular filtration rate (eGFR) and hearing threshold had been measured. We diagnosed CKD as an eGFR <60 mL/min/1.73 m2. The participants were also evaluated for the presence of other risk factors related to kidney dysfunction. °á°ú:The ratio of patients with an eGFR <60 mL/min/1.73 m2 was significantly higher in the hearing loss group compared with the no hearing loss group. After adjustments for age, sex, smoking, alcohol, body mass index, thyroid dysfunction, hemoglobin A1C, blood lipid profile, and blood pressure, the odds ratio (OR) of an eGFR <60 mL/min/1.73 m2 was significantly associated with hearing loss in both ears (OR, 2.50; 95% confidence interval [CI], 1.13–5.53, P = 0.02 in the right ear; OR, 2.58; 95% CI, 1.17–5.69, P = 0.02 on left ear). Among the metabolic parameters for CKD, in addition to serum creatinine, blood pressure was independently associated with an increased hearing threshold (P < 0.01). °á·Ð:The prevalence of eGFR <60 mL/min/1.73 m2 was increased in participants with hearing loss, suggesting that CKD combined with hypertension may play a role in disturbing hearing thresholds.


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